Publications by authors named "C Ruggeri"
Article Synopsis
- - Autophagy is a vital cellular process that helps keep cells healthy by breaking down damaged proteins and organelles, especially during stress, and it's essential in maintaining the endometrium and supporting pregnancy.
- - This process is regulated by various signaling pathways and plays a complex role in preventing tumors by managing cellular homeostasis, but can also promote cancer progression in endometrial carcinoma by supporting nutrient supply for cancer cells.
- - Investigating autophagy's mechanisms and pathways reveals its potential as a therapeutic target in treating endometrial carcinoma, offering hope for effective treatments and overcoming resistance to existing therapies.
Article Synopsis
- Cardiovascular diseases (CVDs) are a major health issue involving various heart-related disorders, and understanding in-hospital mortality rates is important for healthcare improvements and family impacts.
- This study analyzed data from over 6 million hospital admissions, finding an in-hospital mortality rate of 3.01% for patients with CVDs, with diabetes showing a stronger correlation to mortality compared to other risk factors like hypertension and smoking.
- The research utilizes national hospital discharge data to fill gaps in current knowledge about in-hospital mortality related to CVDs, which is vital for ongoing healthcare system development.
Article Synopsis
- Mammalian cells use specific mechanisms to control gene expression, which ultimately affects their characteristics or phenotype.
- Modulating these cellular phenotypes is important for understanding diseases and improving the production of biopharmaceuticals, with CHO and HEK293 cells being key players in therapeutic protein production.
- Recent advancements emphasize the need for precise regulation of gene expression, rather than uncontrolled alterations, and highlight synthetic biology tools that allow for fine-tuned and inducible gene control across various regulatory layers.
Smooth muscle tumors that cannot be histologically classified as leiomyomas or leiomyosarcomas are defined as smooth muscle tumors of uncertain malignant potential. The location of these tumors in the nose is very rare, and the appropriate surgical extent to manage these neoplasms has not been adequately defined. Here we describe the case of a 16-year-old female adolescent who consulted due to a vascular-like tumor in the right nasal cavity who was successfully treated with intranasal surgery.
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