Publications by authors named "C Ruehle"

Article Synopsis
  • Ceftobiprole is a broad-spectrum cephalosporin antibiotic approved for treating pneumonia in adults, and recent studies have explored its use in pediatric populations.
  • Two studies examined its pharmacokinetics and safety in neonates and children up to 17 years, with similar plasma concentration and exposure results compared to adults.
  • The drug was well tolerated, maintaining effective concentrations for a significant period and demonstrating potential effectiveness in achieving pharmacokinetic-pharmacodynamic goals in pediatric patients.
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It now appears likely that commercial entities will carry paying passengers on suborbital spaceflights in this decade. The stresses of spaceflight, the effects of microgravity, and the limited capability for medical care onboard make it advisable to develop a system of medical clearance for such space tourists. The Aerospace Medical Association, therefore, organized a Space Passenger Task Force whose first report on medical guidelines was published in 2001.

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The Armed Forces Institute of Pathology analyzed toxicology specimens on 294 cases submitted by the U.S. Air Force from 1973 through 1984.

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Cases reported to the Armed Forces Institute of Pathology were examined for occupants of helicopters without the crashworthy fuel system (CWFS) who survived crashes but died as a result of postcrash fires. There were 16 fire deaths in the 9 such accidents which occurred between January 1976 and April 1984. All of these victims would have survived if there had been no postcrash fire.

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Helicopter wire-strike accidents usually involve high-voltage lines or telephone wires where the resulting impact is low velocity with minimal loss of occupiable space. Death and injury in these mishaps is often due to blunt force trauma to the head. In a recent wire strike accident investigated by the Division of Aerospace Pathology at The Armed Forces Institute of Pathology, the circumstances suggest that death of both aviators was due to high-voltage electrocution.

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