Publications by authors named "C Roudier Pujol"
Advanced chronic liver disease (ACLD) is associated with a wide spectrum of immune dysfunction. The clinical impact of SARS-CoV-2 on the development of decompensation and immune response in unvaccinated outpatients has not as yet been clearly defined. This study aimed to evaluate the clinical and immunological impact of SARS-CoV-2 on outpatients with ACLD.
View Article and Find Full Text PDFAutism Spectrum Disorders (ASD) are neurodevelopmental disorders whose diagnosis relies on deficient social interaction and communication together with repetitive behaviours. Multiple studies have highlighted the potential of oxytocin (OT) to ameliorate behavioural abnormalities in animal models and subjects with ASD. Clinical trials, however, yielded disappointing results.
View Article and Find Full Text PDFRecently, benchtop nuclear magnetic resonance (NMR) spectrometers utilizing permanent magnets have emerged as versatile tools with applications across various fields, including food and pharmaceuticals. Their efficacy is further enhanced when coupled with chemometric methods. This study presents an innovative approach to leveraging a compact benchtop NMR spectrometer coupled with chemometrics for screening honey-based food supplements adulterated with active pharmaceutical ingredients.
View Article and Find Full Text PDFBackground And Aims: Alcohol relapse after surviving an episode of alcohol-associated hepatitis (AH) is common. However, the clinical features, risk factors, and prognostic implications of recurrent alcohol-associated hepatitis (RAH) are not well described.
Approach And Results: A registry-based study was done of patients admitted to 28 Spanish hospitals for an episode of AH between 2014 and 2021.
Prevalence and clinical impact of alcohol withdrawal syndrome in alcohol-associated hepatitis and the potential role of prophylaxis: a multinational, retrospective cohort study.
EClinicalMedicine
July 2023
Article Synopsis
- The study focused on understanding the prevalence, management, and effects of alcohol withdrawal syndrome (AWS) in patients with alcohol-associated hepatitis (AH) across multiple medical centers in Spain and the USA.
- Of the 432 patients analyzed, 32% experienced AWS, with factors like lower platelet levels and previous AWS history increasing the risk, while prophylaxis reduced it.
- AWS was linked to higher mortality rates and complications such as infections and the need for intensive care, indicating serious implications for patient health after hospitalization.