The first synthesis of the pentacyclic pyridoacridine marine alkaloids: arnoamines A and B.

The synthesis of the marine pyridoacridine alkaloids arnoamines A and B has been accomplished in six and seven steps from 4-chloro-8-methoxy-5-nitroquinoline in 13% and 4% overall yield, respectively.

[Invasive cysticercosis due to Taenia crassiceps in an AIDS patient].

A first case is reported from France of a subcutaneous and muscular tissues invasion by proliferative larval forms of Taenia crassiceps in an AIDS-patient with severe immunodeficiency. These larvae usually develop in rodents whereas the adult form of the cestode is commonly found in foxes. Authors emphasize the differential diagnosis from other human subcutaneous metacestodoses such as T.

[Singular diaphragm-like colonic stricture and short-term administration of a non-steroidal anti-inflammatory drug].

A case of diaphragm-like stricture of the colon induced by non steroidal anti-inflammatory drug (diclofénac LP) is reported in a 65-year-old man who presented abdominal pain. Colonoscopy revealed ulcer in the transverse right colon. The patient gradually developed diaphragm-like stricture in the transverse right colon.