Publications by authors named "C Rothlisberger"

Introduction: Aphasia is a common language disorder acquired after stroke that reduces the quality of life of affected patients. The impairment is frequently accompanied by a deficit in cognitive functions. The state-of-the-art therapy is speech and language therapy but recent findings highlight positive effects of high-frequency therapy.

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Article Synopsis
  • Aphasia is a language disorder that impacts communication abilities, affecting both understanding and expression, which necessitates individualized and adaptive therapy.
  • The project aimed to create a dual-interface system allowing aphasic patients to independently practice language tasks at home while enabling therapists to assign personalized exercises and monitor progress remotely.
  • The study involved 11 therapists and 15 patients, revealing that patients rated the app as excellent in usability, while therapists rated it as good, indicating its effectiveness and acceptance in aphasia therapy.
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In 2015, Switzerland had a population of 8.3 million inhabitants. Since the first coronary angioplasty performed by Andreas Grüntzig in Zurich in 1977, the number of percutaneous procedures has steadily increased.

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Background: Variola virus (family Poxviridae, genus Orthopoxvirus) and the closely related cowpox, vaccinia, and monkeypox viruses can infect humans. Efforts are mounting to replenish the smallpox vaccine stocks, optimize diagnostic methods for poxviruses, and develop new antivirals against smallpox, because it is feared that variola virus might be used as a weapon of bioterrorism.

Methods: We developed an assay for the detection of variola virus DNA.

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An enzyme with a cholinesterase (ChE) activity, produced by Pseudomonas fluorescens, was purified to homogeneity in a three-step procedure. Analysis by non-denaturing and SDS-PAGE, and by isoelectric focusing, indicated that the enzyme was a monomer of 43 kDa, with a pI of 6.1.

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