Publications by authors named "C Rossello"

Ultrasonic-assisted drying is an effective technique for accelerating drying processes, particularly for products with high porosity. The structural changes induced by pulsed electric field (PEF) treatment can make low-porosity products more susceptible to the effects of ultrasound during drying. This study aimed to investigate the influence of PEF treatment on the structure of low-porosity products, such as butternut squash, and to evaluate its effect on ultrasonic-assisted drying.

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Article Synopsis
  • The study evaluates 2-OHOA, a synthetic lipid, in a Phase 1/2A trial to determine its safety, tolerability, and efficacy for treating gliomas and advanced solid tumors in 54 patients.
  • The trial found that 2-OHOA was well-tolerated at dosage levels, with common side effects being mild gastrointestinal issues, while establishing a recommended phase-2 dose of 12,000 mg daily.
  • Some patients, particularly those with high-grade gliomas, showed promising clinical benefits, with 24% experiencing significant positive responses, including one lasting over 2.5 years.
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Pediatric neurological tumors are a heterogeneous group of cancers, many of which carry a poor prognosis and lack a "standard of care" therapy. While they have similar anatomic locations, pediatric neurological tumors harbor specific molecular signatures that distinguish them from adult brain and other neurological cancers. Recent advances through the application of genetics and imaging tools have reshaped the molecular classification and treatment of pediatric neurological tumors, specifically considering the molecular alterations involved.

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This work aimed to evaluate the use of annealing (ANN) ulluco starch in the preparation of biodegradable films and its impact on the physicochemical properties of the materials. Three film samples (FS1, FS2, and FS3) were prepared at a fixed starch concentration (2.6% /) using glycerol as a plasticizer and then compared to a control sample (FSC) prepared with native ulluco starch.

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