Publications by authors named "C Rongieres"
Ovarian response in preimplantation genetic testing for myotonic dystrophy type 1.
J Assist Reprod Genet
December 2024
Purpose: To evaluate ovarian stimulation response in couples undergoing preimplantation genetic testing (PGT-M) for myotonic dystrophy type 1 (DM1) METHODS: Retrospective, observational, multicentric study. Parameters of ovarian response and PGT-M outcomes were compared according to the DM1-affected patient (female or male). A total of 229 couples underwent at least one controlled ovarian hyperstimulation cycle for the PGT-M procedure.
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- * Fifty-two fertility specialists reached an agreement on personalizing gonadotropin dosages according to factors like age and BMI, and preferred fresh transfers for low to normal responders while suggesting freeze-all strategies for high responders.
- * The AMPLITUDE consensus emphasizes the need for optimizing ovarian stimulation protocols in assisted reproductive technology, with recommendations for future research to further enhance treatment outcomes.
Prospective multicenter observational real-world study to assess the use, efficacy and safety profile of follitropin delta during IVF/ICSI procedures (DELTA Study).
Eur J Obstet Gynecol Reprod Biol
February 2024
Article Synopsis
- The study evaluated the use and effectiveness of follitropin delta in women undergoing IVF or ICSI, focusing on its safety and dosing patterns in clinical practice after one treatment cycle.
- Conducted in France across 14 centers, 248 women were treated, with 223 being analyzed; the study highlighted that a significant majority of patients followed a standardized dosing algorithm.
- Key findings included an average of 11.3 oocytes retrieved per patient, a clinical pregnancy rate of 35%, and an ongoing pregnancy rate of 29.6%, indicating good efficacy and safety of follitropin delta in IVF/ICSI treatments.
Objective: To improve the reliability of prediction models for ovarian response to stimulation in ART.
Design: A multicenter retrospective cohort study.
Setting: Twelve reproductive centers.
Background: Cancer treatments of the last decades improve the survival rate of children and adolescents. However, chemo- and radiotherapy result in gonadal damage, leading to acute ovarian failure and sterility. The preservation of fertility is now an integral part of care of children requiring gonadotoxic treatments.
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