Chondroitin Sulfate Nanovectorized by LC-PUFAs Nanocarriers Extracted from Salmon () by Green Process with Decreased Inflammatory Marker Expression in Interleukin-1β-Stimulated Primary Human Chondrocytes In Vitro Culture.

Chondroitin sulfate (CS), a glycosaminoglycan, supports health through various physiological functions, including tissue protection, bone growth, and skin aging prevention. It also contributes to anticoagulant or anti-inflammatory processes, with its primary clinical use being osteoarthritis treatment. This study presents the results of the valorization of lipids and CS, both extracted from salmon co-products through enzymatic processes.

Automated Characterization of Abdominal MRI Exams Using Deep Learning.

Advances in magnetic resonance imaging (MRI) have revolutionized disease detection and treatment planning. However, as the volume and complexity of MRI data grow with increasing heterogeneity between institutions in imaging protocol, scanner technology, and data labeling, there is a need for a standardized methodology to efficiently identify, characterize, and label MRI sequences. Such a methodology is crucial for advancing research efforts that incorporate MRI data from diverse populations to develop robust machine learning models.

Epistaxis Risk in Patients Treated With Left Atrial Appendage Occlusion Versus Oral Anticoagulation.

Introduction: Anticoagulants (AC) are associated with epistaxis in atrial fibrillation (AF) patients. Left atrial appendage occlusion (LAAO) is a treatment that allows AF patients to stop AC. The aim of this study is to evaluate the risk of developing epistaxis following LAAO versus direct oral anticoagulants (DOAC) and warfarin.

Nanoliposome functionalized colloidal GelMA inks for 3D printing of scaffolds with multiscale porosity.

Bioprinting has enabled the creation of intricate scaffolds that replicate the physical, chemical, and structural characteristics of natural tissues. Recently, hydrogels have been used to fabricate such scaffolds for several biomedical applications and tissue engineering. However, the small pore size of conventional hydrogels impedes cellular migration into and remodeling of scaffolds, diminishing their regenerative potential.

Obstructive Sleep Apnea and Chronic Rhinosinusitis: Understanding the Impact of OSA on CRS Disease Burden.

Objective: Assess the impact of obstructive sleep apnea (OSA) on chronic rhinosinusitis (CRS) severeity.

Study Design: Retrospective database review.

Setting: TriNetX US database.