Publications by authors named "C Rodriguez-Garcia"

Propolis is a valuable natural resource for extracting various beneficial compounds. This study explores a sustainable extraction approach for Brazilian green propolis. First, supercritical fluid extraction (SFE) process parameters were optimized (co-solvent: 21.

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The increase in age-related comorbidities, such as cardiometabolic diseases, has become a global health priority. There is a growing need to find new parameters capable of improving the detection of cardiometabolic risk factors, and circulating endocannabinoids (eCBs) are a promising tool in this context. Here, we aimed to investigate the relationship between plasma levels of eCBs and their analogues with body composition and cardiometabolic risk factors in middle-aged adults.

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  • * A newborn, born at 40 weeks, initially appeared healthy but developed severe pulmonary hypertension and respiratory failure shortly after birth, ultimately leading to death within 12 days despite intensive treatment.
  • * Diagnosis was confirmed through surgical lung biopsy and autopsy, which showed consistent histopathological signs; genetic testing revealed a mutation in the FOXF1 gene, also associated with other developmental malformations.
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  • The study investigated the differences in chronic obstructive pulmonary disease (COPD) between genders in patients with alpha-1 antitrypsin deficiency (AATD) using data from the EARCO registry.
  • It analyzed 1283 AATD patients and found that while women reported less smoking and alcohol consumption, they had a higher prevalence of bronchiectasis despite better lung function.
  • Results indicated that women experienced a similar symptom burden as men but had higher rates of exacerbations, suggesting that treatment approaches may need to be adjusted for female patients.
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  • The study investigates the PI*SS genotype's risk for lung disease in individuals with alpha-1 antitrypsin deficiency (AATD) and compares it to the more common PI*ZZ and PI*SZ genotypes.
  • Using data from 1,007 participants, results indicate that individuals with the PI*SS genotype have a lower prevalence of lung diseases like COPD and emphysema compared to PI*ZZ patients, but similar rates to those with the PI*SZ genotype.
  • The findings suggest that while PI*SS is linked to lower lung disease risk than PI*ZZ, it does not show a significant difference when compared to PI*SZ, despite higher serum AAT levels in the former group.
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