Publications by authors named "C Rivers"
Objectives: To develop a reproducible, reliable clinical index of alveolar bone grafting (ABG) outcome based on the eruption position of the cleft canine tooth and determine the association between eruption position and radiographic outcome at 6 months post-grafting.
Methods: Children with complete, non-syndromic, unilateral/bilateral cleft lip and palate in the West of Scotland were identified. Post-ABG radiographic outcome (Kindelan index) and canine eruption position in children with a cleft of the alveolus who had undergone ABG were documented.
Introduction: Previously, we showed that omega-3 polyunsaturated fatty acid n-3 (PUFA) supplementation improved the performance of postpartum rats in the shuttle box escape test (SBET).
Methods: The brains of these rats were used in the current study which examined brain cytochrome c oxidase (CCO) activity in white matter bundles and 39 regions spanning sensorimotor, limbic, and cognitive areas to determine the effects of n-3 PUFAs on neural metabolic capacity and network interactions.
Results: We found that n-3 PUFA supplementation decreased CCO activity in white matter bundles, deep and superficial areas within the inferior colliculus, the anterior and barrel field regions of the primary somatic sensorimotor cortex, the secondary somatic sensorimotor cortex, the lateral, anterior regions of the secondary visual cortex and the ventral posterior nucleus of the thalamus, and the medial nucleus of the amygdala.
Article Synopsis
- - Mineralocorticoid (MR) and glucocorticoid receptors (GR) are key transcription factors involved in various processes like stress response, hormonal signalling, mood, cognition, and memory, despite their structural differences, especially in the N-terminal domain.
- - A study using a Proximity Ligation Assay (PLA) on murine neuroblastoma (N2A) cells showed that continuous stimulation with corticosterone (CORT) results in MR-GR complexes accumulating at the cell nucleus's periphery, particularly when the receptor's ligand binding domain is truncated.
- - Interestingly, while MR-GR complex localization changed with receptor activation, there wasn't a straightforward link between where these complexes were located in the nucleus and