Publications by authors named "C Rivera Quiles"

Study Objectives: Both the (ICSD) and the sleep-wake disorders section of the (DSM) emphasize the importance of clinical judgment in distinguishing the normal from the pathological in sleep medicine. The fourth edition of the DSM (DSM-IV, 1994) introduced the clinical significance criterion (CSC) to standardize this judgment and enhance diagnostic reliability.

Methods: This review conducts a theoretical and historical content analysis of CSC presence, frequency, and formulation in the diagnostic criteria of sleep disorders.

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Article Synopsis
  • Clozapine is effective for treatment-resistant schizophrenia but can cause significant side effects, notably excessive daytime sleepiness, which is a form of hypersomnolence.
  • A systematic review examined how clozapine affects objective measures of hypersomnolence, analyzing six studies using various testing methods like polysomnography (PSG).
  • Initial findings showed clozapine led to longer sleep times and quicker sleep onset, but these effects did not last beyond 4-6 weeks, indicating a need for further long-term research on sleep patterns and wakefulness in clozapine-treated patients.
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Introduction: We aimed to synthesize the information on the risks and benefits of clozapine prescription for resistant challenging behavior in persons with neurodevelopmental disorders.

Methods: Articles were identified with MEDLINE, Web of Sciences, and PsycINFO search from inception through January 2024. The review was restricted to persons with intellectual disability (ID) and/or autism spectrum disorder (ASD) without comorbid psychotic or affective disorder.

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Introduction: Antiseizure medication (ASM) add-on to clozapine may be efficient to target clozapine-resistant mood or psychotic symptoms or clozapine-related adverse drug reactions (ADR) such as seizures. We aimed to synthesize the information relevant for clinical practice on the risks and benefits of clozapine-ASM co-prescription.

Areas Covered: Articles were identified with MEDLINE, Web of Sciences and PsycINFO search from inception through October 2023.

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PATHOPHYSIOLOGICAL HYPOTHESES AND DIAGNOSIS OF INSOMNIA DISORDER. All pathophysiological models place hyperarousal as a central process in the mechanisms of insomnia. These models differ, however, in terms of the importance and role of the variables explaining this hyperarousal.

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