Publications by authors named "C Richard Boland"
Article Synopsis
- The discovery of "mismatch repair proficient (MMRp)-crypt foci" in a patient with constitutional MMR deficiency presents new insights into tumor development in Lynch syndrome (LS).
- The study found MMRp crypts in both non-cancerous and cancerous intestinal tissues, highlighting the unique genetic behavior of MSH6 in tumor formation.
- These findings emphasize the need for careful diagnostic practices when using MMR immunohistochemistry, as the presence of MMRp crypts could lead to misdiagnosis in individuals with CMMRD.
Straintronics leverages mechanical strain to alter the electronic properties of materials, providing an energy-efficient alternative to traditional electronic controls while enhancing device performance. Key to the application of straintronics is bandgap engineering, which enables tuning of the energy difference between the valence and conduction bands of a material to optimize its optoelectronic properties. This mini-review highlights the fundamental principles of straintronics and the critical role of bandgap engineering within this context.
View Article and Find Full Text PDFLinezolid is a critically important antimicrobial used in human medicine. While linezolid is not licensed for food-producing animals, the veterinary use of other antimicrobials, such as phenicols (e.g.
View Article and Find Full Text PDFArticle Synopsis
- Lithium Carbonate is commonly used to treat affective disorders but can lead to various side effects, including a rare condition called Raynaud's phenomenon.
- In a case report, a patient with recurrent depressive disorder developed Raynaud's after starting Lithium, with symptoms disappearing upon stopping the medication and returning when it was resumed.
- While Lithium has been effective for treating vasospastic disorders, this instance demonstrates an unusual negative reaction contrary to its typical efficacy.