A histological investigation on early tissue response to titanium implants in a rat intramedullary model.

Miniature grade 1 titanium screws were inserted in the tibias of 12 mature Wistar rats. Animals were sacrificed at 4, 7, and 21 days postimplantation. A combination of two morphological approaches was used to examine the tissue response to implants.

[Adenocarcinoma in an ileal duplication].

We describe a 54-year-old man with a history of multiple congenital abdominal malformations who developed an adenocarcinoma in a small intestinal duplication. To our knowledge this is the second reported case of an exceedingly rare complication of small intestinal duplication. The relevant literature is reviewed.

Expression and localization of tumor necrosis factor-alpha and its mRNA in idiopathic pulmonary fibrosis.

The expression of tumor necrosis factor alpha and its mRNA was investigated in surgical biopsies from idiopathic pulmonary fibrosis by immunohistochemistry, in situ hybridization, and Northern blotting. Normal areas of lungs resected for cancer were used as controls. Tumor necrosis factor alpha mRNA levels were higher in idiopathic pulmonary fibrosis than in normal lungs as determined by Northern blots.

Cytoskeletal features of alveolar myofibroblasts and pericytes in normal human and rat lung.

Frozen or paraffin-embedded human and rat lung specimens were stained with antibodies against total actin, alpha-smooth muscle (SM) actin, vimentin, desmin, or gelsolin. Alveolar interstitial myofibroblasts [i.e.

Cystic neoplasms of the exocrine pancreas.

Cystic neoplasms of the pancreas are rare and their diagnosis and treatment can be difficult. This report details 7 patients who had histologically proven serous cystadenoma, mucinous cystadenoma and cystadeno carcinoma. Computed tomography and sonography allowed excellent preoperative assessment but to attempt a distinction between the histological variants may be hazardous.