Necrobiosis lipoidica (NL) is a rare granulomatous disorder of unknown etiology which can manifest in ulcerative skin lesions and is widely recognised in association with diabetes mellitus. Our aim was to improve knowledge about the epidemiology and clinical course of NL and evaluate treatment approaches. This multicentre retrospective study covered data from 52 patients with NL of the lower leg, treated between 2006 and 2011.
View Article and Find Full Text PDFStudies of polyspecific associations among African forest primates have primarily focused on arboreal Cercopithecus and Procolobus/Colobus species. We examined the association frequency of the terrestrial drill (Mandrillus leucophaeus) with six sympatric monkey species in Korup National Park, Cameroon, testing reports that Mandrillus associations are infrequent and transient. We conducted 3,284 km of trail walks for 12 months (February-June 2006; July 2007 to January 2008), recording species composition in 612 primate clusters.
View Article and Find Full Text PDFThe therapeutical effect of keto acids on bone histology was investigated in a prospective randomized controlled study of 40 patients. A marked improvement in osteofibrotic as well as in osteomalacic changes was found in bone biopsies after 12 months of treatment with keto acids.
View Article and Find Full Text PDFInfectious mononucleosis, described for the first time many years ago, is still nowadays a frequent disease in children. History, etiology, pathogenesis and immunologic response to infectious mononucleosis are described. The value and limitations of diagnostic tests are discussed.
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