Publications by authors named "C Ramos-Rodriguez"
This study aimed to investigate the association between estimated dietary intake of polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) and human sperm quality. This study cross-sectionally assessed the associations between estimated dietary intake of PCDD/Fs and sperm quality parameters in 200 participants aged 18-40 years from the Led-Fertyl study. Linear regression models, accounting for potential confounding variables, were employed to evaluate the relationships.
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- Elevated levels of fasting plasma total homocysteine (tHcy) and a specific genetic variant (methylenetetrahydrofolate reductase C677T polymorphism) are linked to hypertension, but the role of the l-Arginine pathway was previously unclear.
- A study involving 788 adults found that higher tHcy levels were positively related to two metabolites (ADMA and SDMA) and negatively associated with the l-Arginine/ADMA ratio, indicating a potential protective effect against hypertension.
- The analysis suggested that both tHcy and ADMA play intermediary roles in how the genetic variant affects hypertension risk, highlighting the importance of the l-Arginine pathway in this relationship.
Background: Folate and cobalamin status, although essential for pregnancy, are not routinely monitored in prenatal care.
Objectives: To investigate folate and cobalamin status and determinants throughout pregnancy, in the absence of mandatory folic acid (FA) fortification.
Methods: In a cohort study of 831 mothers recruited at <12 gestational weeks (GW), plasma folate, total homocysteine (tHcy), cobalamin, holotranscobalamin (holoTC), methylmalonic acid (MMA), red blood cell folate (RBCF), and the combined cobalamin status indicator (cB12) were determined at ≤12, 15, 24-27, 34 GW, labor and in the cord.
Background: Little attention has been given to prenatal cobalamin insufficiency in settings where dietary cobalamin intake is presumed adequate, such as populations with habitual intake of foods from animal sources.
Results: However, low cobalamin status in women of fertile age has been reported in Europe, United States, and Canada. In India, where cobalamin deficiency is highly prevalent, it has been associated with an increased risk of miscarriage, intrauterine growth retardation, as well as insulin resistance and lower neurodevelopment scores in the offspring.
Unlabelled: Fibromyalgia syndrome (FMS) is a nonarticular rheumatic syndrome which presents as chronic musculoskeletal pain, stiffness and body aches. FMS affects approximately 2.5% of the population, mostly women.
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