Unexplained dyspnoea is defined as a chronic (≥ 3 months) and significant (mMRC ≥ 2) dyspnoea without a diagnosis after clinical examination, chest X-ray, biological work-up and electrocardiogram. This condition affects 15 % of patients with dyspnoea and is associated with prolonged diagnostic delay and difficulties in patient referral. This article presents the definition and epidemiology of unexplained dyspnoea, as well as the useful elements of the history and clinical examination.
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October 2024
Background: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive diaphragm weakness and deteriorating lung function. Bulbar involvement and cough weakness contribute to respiratory morbidity and mortality. ALS-related respiratory failure significantly affects quality of life and is the leading cause of death.
View Article and Find Full Text PDFBackground: Non-invasive ventilation (NIV) is a standard of care for hypercapnic chronic respiratory failure (CRF). Obstructive sleep apnea syndrome (OSA) frequently contributes to hypoventilation in CRF patients. CPAP improves hypercapnia in selected COPD and obese patients, like NIV.
View Article and Find Full Text PDFBackground: Thoraco-abdominal asynchrony (TAA) is usually assessed by respiratory inductance plethysmography. The main parameter used for its assessment is the calculation of the phase angle based on Lissajous plots. However, there are some mathematical limitations to its use.
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