Publications by authors named "C ROBIN"
Purpose Of Review: Familial Mediterranean Fever (FMF) is a hereditary autoinflammatory disorder predominantly affecting individuals of Mediterranean and Middle Eastern descent, including those with certain heritages including Sephardic Jewish, Armenian, Turkish, and Arab. The disorder affects up to 1 in 200 people making it a very common etiology for pain states worldwide, including serositis mediated painful states of the chest, joint, and abdomen.
Recent Findings: Defined by recurrent episodes of fever and inflammation, FMF can lead to not only severe pain, but complications such as renal amyloidosis, if untreated.
Article Synopsis
- Recent guidelines suggest using quantitative PCR (qPCR) to guide early treatment for toxoplasmosis in patients who received allogeneic hematopoietic cell transplantation (allo-HCT).
- A study analyzing qPCR data from 85 patients found that higher initial parasitic loads were linked to slower clearance and increased mortality risk if patients didn't reach negativity within ten days.
- The findings indicate that monitoring qPCR kinetics can help clinicians identify high-risk patients, prompting potential adjustments to their treatment if necessary.