Successful treatment of adult cherubism with a 60 mg denosumab 6-monthly regimen.

Cherubism is a rare autosomal dominant skeletal dysplasia, affecting the maxilla and/or mandible. The condition typically has childhood onset, followed by progression until puberty, with subsequent regression. Cherubism lesions share histological features with giant cell tumor of bone, where high-dose monthly denosumab is an effective medical treatment.

The potential for glacial flour to impact soil fertility, crop yield and nutrition in mountain regions.

Novel sustainable agricultural strategies that enhance soil nutrients and human nutrition are crucial for meeting global food production needs. Here, we evaluate the potential of "glacial flour," a naturally crushed rock produced by glaciers known to be rich in nutrients (P, K, and micronutrients) needed for plant growth. Our proof-of-concept study, investigated soybean ( var.

NET guidelines for white patients may not fit Asian patients.

Introduction: Pancreatic neuroendocrine tumors (pNETs) are slow growing, malignant tumors that show different survival outcomes by race. Current size-based guidelines were largely developed in White patients. Our aim was to investigate tumor size and incidence of lymph node metastasis (LNM) between White and Asian pNET patients to evaluate generalizability of established guidelines.

Continuous glucose monitoring in pregnant women with pregestational type 2 diabetes: a narrative review.

Type 2 diabetes (T2DM) in pregnancy is associated with poor perinatal outcomes; however, there are limited data on outcomes of continuous glucose monitoring (CGM) use in this population. We reviewed the literature on studies reporting CGM outcomes in pregnant women with T2DM. We aimed to synthesise in a narrative review, the effects of CGM on glycaemic and perinatal outcomes as well as current research gaps.

Metanephrine mirage: distinguishing the phaeocopies, a case report and literature review.

Background: We present one of only seven reported cases of a catecholamine-secreting adrenal neuroblastoma in an adult. The case is used as a platform to discuss key biochemical, genomic and imaging considerations that are central to the successful, targeted management of catecholamine-secreting adrenal tumours.

Case Presentation: A 63-year-old male was urgently reviewed at a tertiary hospital endocrinology outpatient clinic for a 12 cm right-sided adrenal incidentaloma.