Publications by authors named "C R Spray"
The diagnosis of inflammatory bowel disease (IBD) in children and the need to distinguish between subtypes (Crohn's disease (CD) and ulcerative colitis (UC)) requires lengthy investigative and invasive procedures. Non-invasive, rapid, and cost-effective tests to support these diagnoses are needed. Faecal volatile organic compounds (VOCs) are distinctive in IBD.
View Article and Find Full Text PDFNature-based Solutions (NbS) are actions that harness nature to help address major societal challenges. The assessment frameworks for NbS proposed in the literature differ in scope and intended use. In 2020, the International Union for Conservation of Nature (IUCN) introduced their Global Standard for NbS as a framework that can be used by anyone working on different types of NbS.
View Article and Find Full Text PDFFaecal volatile organic compounds differ according to inflammatory bowel disease sub-type, severity, and response to treatment in paediatric patients.
United European Gastroenterol J
July 2024
Article Synopsis
- This study examined the differences in fecal volatile organic compounds (VOCs) in children newly diagnosed with inflammatory bowel disease (IBD) based on disease type and severity.* -
- Researchers found that 43.6% of the VOCs were significantly decreased in children with Crohn's disease and ulcerative colitis, particularly certain fatty acids and alcohols, indicating a unique profile related to IBD.* -
- Despite clinical improvements with treatment, the overall number and amounts of VOCs did not increase, highlighting ongoing dysbiosis, with specific compounds showing distinct changes linked to treatment outcomes.*
Research has demonstrated positive relationships between fundamental movement skills (FMS) and mathematics achievement in children, and this relationship may be mediated by spatial ability. Engaging in physical activity (PA) may also have positive outcomes on mathematics achievement; however, no study has investigated this network of relationships together. This study aimed to examine the relationship between PA and mathematics achievement, and the mediating effects of FMS and spatial abilities, in primary school children.
View Article and Find Full Text PDFBackground: Pediatric inflammatory bowel disease (pIBD) incidence has increased over the last 25 years. We aim to report contemporaneous trends across the South West United Kingdom.
Methods: Data were provided from centers covering the South West United Kingdom (Bristol, Oxford, Cardiff, Exeter, and Southampton), with a total area at-risk population (<18 years of age) of 2 947 534.