Describing Anisocoria in Neurocritically Ill Patients.

Background: Anisocoria (unequal pupil size) has been defined using cut points ranging from greater than 0.3 mm to greater than 2.0 mm for absolute difference in pupil size.

A systematic review of randomised controlled trials with adaptive and traditional group sequential designs - applications in cardiovascular clinical trials.

Background: Trial design plays a key role in clinical trials. Traditional group sequential design has been used in cardiovascular clinical trials over decades as the trials can potentially be stopped early, therefore, it can reduce pre-planned sample size and trial resources. In contrast, trials with adoptive designs provide greater flexibility and are more efficient due to the ability to modify trial design according to the interim analysis results.

Barriers and facilitators of noncommunicable disease (NCD) prevention in Kerala: A qualitative study.

Context: The burden of noncommunicable diseases (NCD) is increasing at an alarming rate, contributing to about 23% of the mortality in the rural and 30% of the total mortality in the urban population in India. Even with high health literacy in Kerala, the state has higher rates of NCD risk factors and lower diabetes and hypertension control rates.

Aims: The objectives were to qualitatively assess the facilitators and barriers of NCD prevention from the patients' and health care providers' perspectives and assess the perceptions of healthy lifestyle behaviors among NCD risk persons and patients.

Inter-device reliability of the NPi-100 pupillometer.

The purpose of this study was to explore the inter-device reliability of NPi-100 pupillometers (NeuroOptics, Inc.). The pupillary examination is a fundamental element of the neurological exam.