Publications by authors named "C R SHEFFIELD"

Article Synopsis
  • Septic shock leads to increased end-diastolic volume (EDV) and decreased ejection fraction in survivors, unlike nonsurvivors, whose EDV does not increase due to more severe diastolic dysfunction early in the condition.* -
  • In a study with beagles, findings indicate that septic animals experienced significant heart issues, including wall edema and thinning, resulting in decreased heart performance, particularly in nonsurvivors during the initial phase of sepsis.* -
  • The research suggests that cardiac dysfunction during sepsis is connected to microvascular injury and edema, with important implications for understanding heart changes and recovery in septic patients.*
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Article Synopsis
  • Septic shock causes significant cardiac dysfunction in both humans and animal models, characterized by increased biventricular end diastolic volume and decreased ejection fraction, with these abnormalities developing over the course of two days and generally reversing by day ten.
  • In a study involving purpose-bred beagles, septic animals showed greater left ventricular wall edema and dysfunction compared to controls, with non-survivors displaying more severe changes in cardiac function and size.
  • The differential changes in cardiac volume and function between survivors and non-survivors suggest that septic shock impacts heart performance significantly, but the exact mechanisms behind these differences remain unclear.
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Background: National prevalence rates for obesity and heart failure (HF) have been steadily increasing, which predisposes patients to higher morbidity and mortality rates.

Objectives: The purpose of this study was to evaluate the prevalence of HF stages in hospitalized patients according to their body mass index (BMI).

Setting: Academic institution.

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Objectives: To demonstrate varying degrees of immediate postoperative figure of 8 deformity following three different methods of tracheal suturing.

Study Design: Comparative ex-vivo study.

Methods: A fresh, unfixed rabbit trachea was harvested and bisected at its midpoint.

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The genus Ancyloscelis Latreille, 1829 (Hymenoptera: Apidae), a taxon restricted to the Neotropics and southern Nearctic (Michener 1942, 2000, 2007; Schaller and Roig-Alsina 2021; Melo 2022), has been difficult to place precisely within the higher classification of bees (Roig-Alsina and Michener 1993; Aguiar et al. 2019; Freitas et al. 2020), and even the genus name has a confusing history (see Michener 1942).

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