Publications by authors named "C R Osorio"
Article Synopsis
- The study discovered a new genomic island (pddGI-1) in the marine pathogen Photobacterium damselae, located on chromosome II.
- This genomic island shares features with other islands in Vibrio species and consists of genes for antioxidant defense, energy metabolism, and systems that modify DNA.
- The pddGI-1 also includes a complete system for vibroferrin, which helps the bacteria thrive in low-iron environments, suggesting that strains with this island have a growth advantage in such conditions.
Article Synopsis
- - Ferritin is an important protein for iron storage in the brain, but mutations in its light chains can lead to neuroferritinopathy, a rare disease with limited information available.
- - This study explored how different mutations in ferritin alter its structure and biochemical properties using bioinformatics tools and machine learning models.
- - The A96T mutation was found to reduce the size of ferritin's entry holes, which may impair its function and result in increased iron release in the brain, potentially contributing to neurodegeneration.
Article Synopsis
- * This study focuses on incorporating varying percentages of bio-based polyurethane (PU) into cementitious mortar, with 2% PU showing impressive gains in compressive strength, flexural strength, and initial flow performance after 28 days.
- * The research demonstrates that bio-based PU not only improves the mechanical properties of cementitious mortars but also establishes strong interfacial bonds, suggesting its potential as an eco-friendly option for industrial flooring applications.
Article Synopsis
- Call-handlers and dispatchers (CHDs) in emergency services are vital for public safety but are at a higher risk for mental health issues like PTSD, depression, anxiety, and alcohol misuse.
- A study aimed to estimate the global prevalence of these mental health conditions among CHDs through a thorough review of existing research.
- The findings revealed significant prevalence rates: 17.8% for PTSD, 28.2% for depression, 17.2% for anxiety, and 17.8% for hazardous drinking, suggesting an urgent need for more research and psychological support for these professionals.
Background: To compare Gleason 7 (3+4) and (4+3) prostatic adenocarcinoma (PC) with different prognostic criteria through immunohistochemical analysis with anti-PSA, anti-Ki 67 and anti-AMARC antibodies.
Methods: We analyzed 221 surgical specimens from patients between 40 and 86 years-old (mean=63) with PC. The immunohistochemical study was performed with anti-PSA, anti-Ki 67 and anti-AMARC.