Prognostic value of changes in vibration-controlled transient elastography parameters for liver, cardiovascular and mortality outcomes in individuals with type 2 diabetes and metabolic dysfunction-associated steatotic liver disease: The Rio de Janeiro type 2 diabetes cohort.

Background/aims: The prognostic importance of changes in vibration-controlled transient elastography (VCTE) parameters, liver stiffness measurement (LSM), and controlled attenuation parameter (CAP), in individuals with type 2 diabetes (T2D) and metabolic dysfunction-associated steatotic liver disease (MASLD) is unknown.

Methods: A prospective cohort of 288 patients underwent 2 VCTE exams at least 2 years apart, and the relative percentage changes in LSM and CAP were calculated. Outcomes were the occurrence of any liver-related events (LREs), cardiovascular events (CVEs), and all-cause mortality.

Essential oil and aqueous extract of basil (Ocimum basilicum) in the diet of pacu (Piaractus mesopotamicus).

This study aimed to evaluate the effects of Ocimum basilicum supplementation in the diet for Piaractus mesopotamicus regarding productive performance, intestinal morphology, muscle residue, and hematological changes after simulated transport stress. Juvenile (23 g±0.08, n = 180) were stocked into 300-L tanks in three treatments and six replicates each: a control diet (not supplemented), a diet with 0.

Impact of Daytime and Nighttime Blood Pressure and Nocturnal Blood Pressure Fall on Heart Failure Risk in Treated Hypertension.

Background: To evaluate the impact of daytime, nighttime and nocturnal blood pressure (BP) fall on heart failure (HF).

Methods: We analyzed data of five cohorts including 15,526 treated hypertensive patients, experiencing 625 HF events, by study-level meta-analysis. The pooled hazard ratios (HR) and 95% confidence intervals (CI) for 1-SD increase in BP parameters or per group were calculated.

Syndecan-1 and E-Cadherin Expression in Canine Cutaneous Squamous Cell Carcinoma.

Cutaneous squamous cell carcinoma (CSCC) in dogs is a locally invasive tumor that typically occurs in areas of poorly pigmented skin due to sun exposure. Identifying new biomarkers, such as syndecan-1 (CD138) and E-cadherin, is fundamental for tumor diagnosis and prognosis. Dysregulation of syndecan-1, expressed in epithelial tissue, fibroblasts, and plasma cells, is associated with poor prognosis in several types of cancer.

Magnetic seizure therapy for unipolar and bipolar depression: An up to date systematic review.

Background: Magnetic seizure therapy (MST) has emerged as a promising alternative to electroconvulsive therapy (ECT) for treatment-resistant depression. Previous systematic reviews and meta analysis already showed its primary results, however, there are no recent reviews updating these findings.

Objectives: This systematic review aimed to make an updated systematic review of MST on unipolar and bipolar depression.