Toward Resolving Heterogeneous Mixtures of Nanocarriers in Drug Delivery Systems through Light Scattering and Machine Learning.

Nanocarriers (NCs) have emerged as a revolutionary approach in targeted drug delivery, promising to enhance drug efficacy and reduce toxicity through precise targeting and controlled release mechanisms. Despite their potential, the clinical adoption of NCs is hindered by challenges in their physicochemical characterization, essential for ensuring drug safety, efficacy, and quality control. Traditional characterization methods, such as dynamic light scattering and nanoparticle tracking analysis, offer limited insights, primarily focusing on particle size and concentration, while techniques like high-performance liquid chromatography and mass spectrometry are hampered by extensive sample preparation, high costs, and potential sample degradation.

Recovery Following Recurrent Fires Across Mediterranean Ecosystems.

In fire-prone regions such as the Mediterranean biome, fire seasons are becoming longer, and fires are becoming more frequent and severe. Post-fire recovery dynamics is a key component of ecosystem resilience and stability. Even though Mediterranean ecosystems can tolerate high exposure to extreme temperatures and recover from fire, changes in climate conditions and fire intensity or frequency might contribute to loss of ecosystem resilience and increase the potential for irreversible changes in vegetation communities.

The Effectiveness of Psychological Intervention for Women Who Committed Child Sexual Abuse: An Empty Systematic Review.

The topic of sex offenses committed by women has received relatively little attention until recent decades. The scarcity of research in this domain underscores the urgent need for a more comprehensive understanding and effective interventions. Women who committed child sexual abuse (CSA) exhibit a distinct psychological profile compared to men, requiring specific intervention programs.

Co-occurrence of marine and atmospheric heatwaves with drought conditions and fire activity in the Mediterranean region.

Climate change has become a major concern in the twenty-first century, leading to the amplification of extreme events and, consequently, to severe impacts on society, economy and ecosystems. Heatwave conditions in particular, often coupled with extended periods of dryness, have an important contribution in exacerbating rural fires. Here, we propose to analyse the co-occurring interplay between atmospheric heatwaves and droughts in southern Europe, and marine heatwaves in the East Atlantic and the Mediterranean Sea, between 2001 and 2022, highlighting their linkage to wildfires, on both an individual and compound approach.