Publications by authors named "C R Bunn"
Determining how alveoli are formed and maintained is critical to understanding lung organogenesis and regeneration after injury. To study the cellular dynamics of this critical stage of lung development, we have used scanned oblique-plane illumination microscopy of living lung slices to observe alveologenesis in real time at high resolution over several days. Contrary to the prevailing notion that alveologenesis occurs by airspace subdivision via ingrowing septa, we find that alveoli form by ballooning epithelial outgrowth supported by contracting mesenchymal ring structures.
View Article and Find Full Text PDFBackground: To explore continuities and changes in gambling behaviour during the COVID-19 pandemic and the factors that influenced these among a sample of regular sports bettors.
Methods: A longitudinal qualitative study using in-depth interviews. Sixteen sports bettors living in Britain took part in the first interviews in July-November 2020, and 13 in the follow-up interviews in March-September 2021.
The increased prevalence of non-communicable diseases (NCDs) in recent years has led many Low- and Middle-Income Countries (LMICs), including Tanzania, to develop policies to manage their burden. Musculoskeletal (MSK) conditions, such as arthritis, account for 20% of all years lived with disability in LMICs, but the NCD strategies rarely address them. There is substantial research on the disruption MSK conditions cause to people's lives within High-Income Countries, but very little is known about the lived experiences in LMICs.
View Article and Find Full Text PDFArticle Synopsis
- * This study employed eight focus groups in Malawi to explore the perspectives of breastfeeding women, couples, and healthcare providers on the collection of these "non-invasive" biosamples, revealing varying perceptions of invasiveness.
- * Findings indicate a disconnect between biomedical views of "non-invasive" sampling and community concerns, underscoring the need for researchers to address therapeutic misconceptions and engage openly with the communities involved in biosampling.