Publications by authors named "C R Balistreri"

Inflammatory bowel diseases (IBD) are chronic inflammatory and pathological conditions of the gastrointestinal tract, which include two main clinical subtypes: Crohn's disease (CD) and ulcerative colitis (UC). IBDs show an increase in their age-standardized global incidence rate worldwide, with no gender differences, although the age-standardized mortality rate has decreased over the years. Indeed, thanks to recent therapies with novel mechanisms of action, including those with biologics and small molecules, it has been possible to reduce the mortality rate of IBDs.

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Predicting the onset, progression, and outcome of rare and chronic neurological diseases, i.e. neuromuscular diseases, is an important goal for both clinicians and researchers and should guide clinical decision-making and personalized treatment plans.

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Article Synopsis
  • Systemic inflammation raises the risk of mortality in hospitalized older patients, especially in the context of age-related diseases and infections like COVID-19.
  • Inflammatory biomarkers such as the C-reactive protein to albumin ratio (CAR) and various prognostic scores (GPS, mGPS, hs-mGPS) effectively predict short-term mortality but are often underused for this purpose.
  • The study involving 3,206 geriatric patients found that higher CAR and higher GPS scores significantly correlated with increased mortality risk, especially in men, indicating that these inflammatory markers can help assess in-hospital mortality risk in older adults.
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