Publications by authors named "C Quintini"

Small-for-size syndrome poses a significant challenge in living donor liver transplantation, with potentially severe consequences including liver failure and death. This review explores the management strategies for SFSS, starting from the pathophysiology of the disease. SFSS arises from insufficient liver mass in the graft and hyperdynamic circulation in cirrhotic recipients, leading to portal hyperperfusion and subsequent liver injury.

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Article Synopsis
  • This study investigated the impact of Flavin Mononucleotide (FMN) levels in the flush solution used during liver cold storage on transplant outcomes, involving 62 liver transplant recipients.
  • The results showed that higher FMN levels were linked to worse graft survival rates, with the low-FMN group having a 100% one-year survival compared to 77% for the high-FMN group.
  • The study concluded FMN level is a reliable biomarker for predicting post-transplant success, suggesting that strategies like machine perfusion could improve outcomes for livers with high FMN levels.
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  • The study focuses on a surgical technique to address venous thrombosis that can occur after uterus transplantation (UTx), which is a treatment for uterine factor infertility.
  • A case report describes the successful intervention in a 30-year-old woman who developed intraoperative thrombosis after receiving a uterus from a brain-dead donor.
  • The innovative "Y-shaped" venous jump graft restored venous outflow, leading to a successful pregnancy and the delivery of a healthy infant, marking a significant advancement in UTx procedures.
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Obesity is a risk factor for kidney, liver, heart, and pulmonary diseases, as well as failure. Solid organ transplantation remains the definitive treatment for the end-stage presentation of these diseases. Among many criteria for organ transplant, efficient management of obesity is required for patients to acquire transplant eligibility.

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