Experience and Perspectives on Antibacterial Therapy for Listeriosis in a Tertiary Teaching Hospital in China: A Retrospective Study and Health Care Provider Survey.

Listeriosis is a rare, life-threatening bacterial infection. Prompt, appropriate antibiotic treatment is essential to save lives. We aimed to investigate antibiotic selection and listeriosis knowledge among health care providers.

Direct Photocatalytic Oxidation of Methane to Formic Acid with High Selectivity via a Concerted Proton-Electron Transfer Process.

Light-driven direct conversion of methane to formic acid is a promising approach to convert methane to value-added chemicals and promote sustainability. However, this process remains challenging due to the complex requirements for multiple protons and electrons. Herein, we report the design of WO-based photocatalysts modified with Pt active sites to address this challenge.

Laser Fabrication and Performance of Flexible Pressure Sensors with Ridge-Mimicking Spatially Ordered Microstructures.

The proliferation of flexible pressure sensors has generated new demands for high-sensitivity and low-cost sensors. Here, we propose an elegant strategy to address this challenge by taking a ridge-mimicking, gradient-varying, spatially ordered microstructure as the sensing layer, with laser processing and interdigitated electrodes as the upper and lower electrode layers. Simultaneously, the entire structure is encapsulated with polyimide (PI) tape for protection, and the fabrication process is relatively feasible, facilitating easy scaling.

The Chemical Structure and Pharmacological Activity of Sesquiterpenoids in Sw.

is one of the most important orchids with high medicinal value. The diverse pharmacological activities of are attributed to its rich content of secondary metabolites. Due to the high variety and content of sesquiterpenoids in , more studies on their pharmacological activities have been reported.

Chemokine CXCL12 Activates CXC Receptor 4 Metastasis Signaling Through the Upregulation of a CXCL12/CXCR4/MDMX (MDM4) Axis.

Background: The metastasis-promoting G-protein-coupled receptor CXC Receptor 4 (CXCR4) is activated by the chemokine CXCL12, also known as stromal cell-derived factor 1 (SDF-1). The CXCL12/CXCR4 pathway in cancer promotes metastasis but the molecular details of how this pathway cross-talks with oncogenes are understudied. An oncogene pathway known to promote breast cancer metastasis in MDA-MB-231 xenografts is that of Mouse Double Minute 2 and 4 (MDM2 and MDM4, also known as MDMX).