Publications by authors named "C Putterman"
Objectives: To evaluate urinary activated leucocyte cell adhesion molecule (ALCAM) and CD6 as predictors of lupus nephritis (LN) progression or disease resolution across a 1-year study.
Methods: Serum and urine samples from biopsy proven LN subjects (n = 122) were prospectively collected over the course of a year at 3- or 6-month intervals (weeks 0, 12, 26, and 52) across multiple study sites and assessed for soluble ALCAM and CD6 levels. Urine creatinine from the same urine sample was used to normalize the levels of urinary ALCAM and urinary CD6.
Introduction: Approximately 20-40% of patients with systemic lupus erythematosus (SLE) experience neuropsychiatric SLE (NPSLE), which often manifests as cognitive dysfunction and depression. Currently, there are no approved treatments for NPSLE because its underlying mechanisms are unclear. Identifying relevant mediators and understanding their contribution to pathogenesis are crucial for developing targeted treatment options.
View Article and Find Full Text PDFDevelopment of MyREADY Transition BBD Mobile App, a Health Intervention Technology Platform, to Improve Care Transition for Youth With Brain-Based Disabilities: User-Centered Design Approach.
JMIR Pediatr Parent
October 2024
Background: Transition from pediatric to adult health care varies and is resource intensive. Patient-centered health information technology (HIT) interventions are increasingly being developed in partnership with patients.
Objective: This study aims to develop an internet-based mobile app intervention for patients with brain-based disabilities to improve transition in care readiness.
Article Synopsis
- The Manhattan Lupus Surveillance Program (MLSP) investigated cardiovascular disease events in systemic lupus erythematosus (SLE) patients and compared their rates to population controls based on sex, age, and race/ethnicity.
- In a study of 1,285 SLE patients, 13.9% experienced cardiovascular events, with higher risks associated with being male and over the age of 60.
- The study found that Hispanic/Latino and non-Hispanic Black patients had significantly elevated risks for cardiovascular events compared to other racial groups, highlighting a higher overall prevalence of these events among SLE patients compared to the general population.
Background: Since 2011 when the Canadian Institutes of Health Research launched the Strategy for Patient Oriented Research, there has been a growing expectation to embed patient-oriented research (POR) in the health research community in Canada. To meet this expectation and build capacity for POR in the field of neurodevelopmental disability and child health, in 2017 researchers and family leaders at CanChild Centre for Childhood Disability Research, McMaster University partnered with Kids Brain Health Network and McMaster Continuing Education to develop and implement a 10-week online Family Engagement in Research (FER) Course.
Main Text: From its inception, the FER Course has been delivered in partnership with family leaders and researchers.