Publications by authors named "C Porcher"

Heavy mineral deposits occur in several coastal areas of the world, formed over a long period due to variations in mean sea level, wave action, and winds. These are the main sources of ilmenite (FeTiO3), which in turn is the source of more than 80% of the TiO2 produced and applied in various industries, most recently in nanotechnology. The present study mapped heavy mineral deposits on the coast of Rio Grande do Sul in southern Brazil using integrated proximal and orbital thermal infrared (TIR) remote sensing techniques.

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Article Synopsis
  • The effectiveness of inhibitory neurotransmission in neurons is influenced by chloride levels, which are controlled by cation-chloride cotransporters NKCC1 and KCC2, with brain-derived neurotrophic factor (BDNF) playing a significant role in their function.
  • This study explored how both precursor BDNF (proBDNF) and mature BDNF (mBDNF) affect chloride regulation in immature rat neurons and their impact on behavior, finding that both forms inhibit chloride extrusion.
  • Results indicate that proBDNF enhances the endocytosis of KCC2 and causes sensory and behavioral issues in developing rats, highlighting BDNF's important role in regulating chloride transport and inhibitory synaptic transmission.
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Haematopoietic stem and progenitor cells emerge from specialized haemogenic endothelial cells in select vascular beds during embryonic development. Specification and commitment to the blood lineage, however, occur before endothelial cells are endowed with haemogenic competence, at the time of mesoderm patterning and production of endothelial cell progenitors (angioblasts). Whilst early blood cell fate specification has long been recognized, very little is known about the mechanisms that induce endothelial cell diversification and progressive acquisition of a blood identity by a subset of these cells.

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In the early stages of the central nervous system growth and development, (GABA) plays an instructive trophic role for key events including neurogenesis, migration, synaptogenesis, and network formation. These actions are associated with increased concentration of chloride ions in immature neurons [(Cl)] that determines the depolarizing strength of ion currents mediated by GABA receptors, a ligand-gated Cl permeable ion channel. During neuron maturation the (Cl) progressively decreases leading to weakening of GABA induced depolarization and enforcing GABA function as principal inhibitory neurotransmitter.

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In November 2015, the collapse of the Fundão dam (Minas Gerais, Brazil) carried over 40 × 10 m of iron ore tailings into the Doce river and caused massive environmental and socioeconomic impacts across the watershed. The downstream mudslide scavenged contaminants deposited in the riverbed, and several potentially toxic elements were further released through reduction and solubilization of Fe oxy-hydroxides under estuarine conditions. A turbidity plume was formed off the river mouth, but the detection of contaminants' dispersion in the ocean remains poorly assessed.

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