Agenesis of the dorsal pancreas.

During the last 100 years in medical literature, there are only 54 reports, including the report of Pasaoglu et al (World J Gastroenterol 2008; 14: 2915-2916), with clinical descriptions of agenesis of the dorsal pancreas in humans. Agenesis of the dorsal pancreas, a rare congenital pancreatic malformation, is associated with some other medical conditions such as hyperglycemia, abdominal pain, pancreatitis and a few other diseases. In approximately 50% of reported patients with this congenital malformation, hyperglycemia was demonstrated.

Agenesis of the dorsal pancreas and associated diseases.

Background: Agenesis of the dorsal pancreas is a very rare congenital pancreatic malformation and is associated with some other diseases.

Methods: A PubMed search revealed 53 cases of agenesis of the dorsal pancreas.

Results: In 28 patients with this congenital malformation hyperglycemia was demonstrated, 27 had abdominal pain, 16 had pancreatitis, 14 had an enlarged or prominent pancreatic head visible on computed tomography, and in a few cases, polysplenia, which may occur with various congenital anomalies of visceral organs, was described.

Evaluation of conditions associated with glycated hemoglobin values below the reference range.

Background: Evaluation of conditions associated with glycated hemoglobin (HbA1c) values below the reference range in HbA1c determinations.

Methods: Over a time period of 5 years, HbA1c results were determined with the ion-exchange high-performance liquid chromatography (HPLC) method HA-8140 Menarini.

Results: Of approximately 20 000 HbA1c results analyzed, 9 were below the reference range.