Publications by authors named "C Pindado-Ortega"
Low-dose oral minoxidil for frontal fibrosing alopecia: a 122-patient case series.
Actas Dermosifiliogr
November 2024
Article Synopsis
- * Out of 122 patients, 45.1% reported subjective improvements in hair density at the frontotemporal hairline, with varying degrees of improvement noted.
- * While 57.4% of patients saw overall hair density improvements, 33.6% experienced adverse effects, primarily hypertrichosis; however, the findings suggest that oral minoxidil can enhance hair and eyebrow growth in FFA patients.
Background: Androgenetic alopecia (AGA) is common. While topical minoxidil remains the only FDA-approved therapeutic for AGA, its efficacy is limited in stimulating clinically significant hair regrowth over the longer term. Oral minoxidil, which is used off-label, is a promising alternative; however, its effectiveness and underlying mechanisms warrant further investigation.
View Article and Find Full Text PDFBackground And Objective: Systemic adverse effects (AE) are a major concern of low-dose oral minoxidil (LDOM) treatment, especially in patients with arterial hypertension or arrhythmia. The objective of this study was to evaluate the safety of LDOM in patients with hypertension or arrhythmia.
Patients And Methods: Retrospective multicenter study of patients with hypertension or arrhythmia treated with LDOM for any type of alopecia.
Genotyping of the rs1800440 Polymorphism in CYP1B1 Gene and the rs9258883 Polymorphism in HLA-B Gene in a Spanish Cohort of 223 Patients with Frontal Fibrosing Alopecia.
Acta Derm Venereol
September 2023
The pathogenesis of frontal fibrosing alopecia has been linked to specific genetic variants. CYP1B1 codes for a component of the cytochrome p450 machinery that is involved in the metabolism of xenobiotic oestrogens. The study of the prevalence of polymorphisms in this gene may help to understand their role in the development of frontal fibrosing alopecia.
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