Publications by authors named "C Peyrefitte"
Article Synopsis
- - cVDPV3s were found in wastewater samples in French Guiana between May and August 2024, indicating the detection of circulating type 3 vaccine-derived polioviruses.
- - The oral polio vaccine isn’t used in the area, suggesting these polioviruses may have been imported or derived from a vaccine strain.
- - This situation emphasizes the need for environmental monitoring to catch and eliminate any hidden poliovirus activity, which is vital for the global polio eradication effort.
Dugbe orthonairovirus (DUGV) is a tick-borne arbovirus within the order Although displaying mild pathogenic potential, DUGV is genetically related to the Crimean-Congo hemorrhagic fever virus (CCHFV), another orthonairovirus that causes severe liver dysfunction and hemorrhagic fever with a high mortality rate in humans. As we previously observed that CCHFV infection could massively recruit and lipidate MAP1LC3 (LC3), a core factor involved in the autophagic degradation of cytosolic components, we asked whether DUGV infection also substantially impacts the autophagy machinery in epithelial cells. We observed that DUGV infection does impose LC3 lipidation in cultured hepatocytes.
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- A lot of money has been spent on studying the COVID-19 virus in Africa, leading to over 100,000 virus samples being analyzed to understand the spread of the disease.
- *More countries in Africa are now able to do these studies themselves, which helps them get results faster and keep a close watch on the virus.
- *To keep fighting COVID and other diseases, more funding and support for testing and research in Africa is really important for the future.