We studied the efficacy of propafenone in 16 patients (pts) with exercise-induced ventricular arrhythmias (VA). Propafenone was given in doses of 450 mg (13 pts) to 900 mg (3 pts) per day and was compared with placebo. An arrhythmic index was calculated by dividing the frequency and severity of VA by the duration of exercise test (in min).
View Article and Find Full Text PDFMany factors have been found to influence the magnitude of ST-segment depression in the exercise electrocardiogram. We investigated whether R-wave amplitude is a significant factor. We studied the exercise electrocardiogram of 20 patients with angiographically documented coronary artery disease, including greater than or equal to 70% stenosis of the left anterior descending artery, who had an ischemic response to exercise but no previous anterior myocardial infarction.
View Article and Find Full Text PDFDissociation between duration of electrical and mechanical systole has been seen with increase of myocardial shortening velocity or adrenergic activity. We found a decrease of the QS2/QT ratio after exercise in 10 pts with semisitting bicycle maximal exercise test and a normal radionuclide angiogram. No change was seen in 9 patients with a normal study with beta blockade, and in pts with a abnormal radionuclide test, without beta blockade (11 pts).
View Article and Find Full Text PDFWe compared the response to a modified Bruce treadmill exercise (EX) protocol lasting 7 min in 5 groups of male individuals free of clinical heart disease: I (age less than 35 years, N = 12), II (age 35-44 years, N = 10), III (age 45-54 years, N = 13), IV (age 55-64 years, N = 13) and V (age greater than 65, mean 70.35 +/- 4.67 years, N = 20).
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