Quantifying accuracy and precision from continuous response data in studies of spatial perception and crossmodal recalibration.

The ability to detect the absolute location of sensory stimuli can be quantified with either error-based metrics derived from single-trial localization errors or regression-based metrics derived from a linear regression of localization responses on the true stimulus locations. Here we tested the agreement between these two approaches in estimating accuracy and precision in a large sample of 188 subjects who localized auditory stimuli from different azimuthal locations. A subsample of 57 subjects was subsequently exposed to audiovisual stimuli with a consistent spatial disparity before performing the sound localization test again, allowing us to additionally test which of the different metrics best assessed correlations between the amount of crossmodal spatial recalibration and baseline localization performance.

Deep brain pulse-generator and lead-extensions: subjective sensations related to measured parameters.

This study analyzed subjective sensations caused by DBS pulse-generator and lead-extensions in relation with objectively measured parameters. In 50 patients implant-related sensations were evaluated. The pulse-generator mobility was video-analyzed.

The TOM core complex: the general protein import pore of the outer membrane of mitochondria.

Translocation of nuclear-encoded preproteins across the outer membrane of mitochondria is mediated by the multicomponent transmembrane TOM complex. We have isolated the TOM core complex of Neurospora crassa by removing the receptors Tom70 and Tom20 from the isolated TOM holo complex by treatment with the detergent dodecyl maltoside. It consists of Tom40, Tom22, and the small Tom components, Tom6 and Tom7.

Similar effects of pulsatile and constant intravenous insulin delivery.

Effects of constant and pulsatile i.v. insulin delivery were examined in seven healthy subjects by means of euglycemic clamp technique.