Publications by authors named "C Pautas"
Despite recent refinements in the diagnostic and prognostic assessment of CEBPA mutations in AML, several questions remain open, i.e. implications of different types of basic region leucin zipper (bZIP) mutations, the role of co-mutations and the allelic state.
View Article and Find Full Text PDFLong-term outcome after autologous -negative peripheral blood stem cell transplantation in adults with Philadelphia-positive acute lymphoblastic leukemia: a comparative study.
Leo Caillot Mathieu Leclerc Emmanuel Jacques Raphael Sleiman Ivan Sloma Orianne Wagner-Ballon Cecile Pautas
Haematologica
April 2024
Article Synopsis
- A study assessed the safety and efficacy of gilteritinib in 167 patients with relapsed/refractory FLT3-mutated acute myeloid leukemia (AML), comparing it to data from the ADMIRAL trial.
- The key differences in patient characteristics included higher rates of poor performance status and FLT3-TKD mutations, along with more complex treatment histories among participants.
- The results showed similar rates of complete remission and overall survival between treatment cohorts and highlighted the potential for outpatient treatment benefits for heavily pretreated patients.