Publications by authors named "C Patrick McAtee"

Background/objectives: Kaposi sarcoma (KS) is a common lymphatic endothelial cancer among children with and without HIV in central and eastern Africa. Despite its clinical heterogeneity, its various clinical phenotypes are often grouped together in staging and treatment algorithms. Patients with KS tumor-associated edema, referring to hard, non-pitting lesions which often lead to chronic disability, represent a unique, understudied subgroup of children with KS.

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Context: The integration of certified community health workers (CCHWs) with specialty chronic disease training into clinical care teams has demonstrated improvements in chronic disease quality of care, management, and outcomes.

Program: Rhode Island Department of Health's Diabetes, Heart Disease, and Stroke Program expanded the roles of CCHWs employed by Community Health Teams for chronic disease with a focus on cardiovascular disease (CVD) and diabetes mellitus (DM) from 2020 to 2023. Rhode Island Department of Health's Diabetes, Heart Disease, and Stroke Program sought to determine whether patient health behaviors and clinical outcomes improved with specialty trained CCHW support.

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Article Synopsis
  • The study explores how fluorescent proteins (FPs) can be used to track proteins in live cells, highlighting limitations when FPs label all protein pools.
  • To address this, the research introduces bioconjugate tags known as fluorogen activation proteins (FAPs), which enable selective visualization of specific protein subpopulations.
  • The researchers optimized FAP technology for use in yeast, successfully tagging a G-protein coupled receptor to examine its behavior in response to external signals, enhancing the potential applications of FAPs in cellular studies.
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