Publications by authors named "C Pastorino"
Article Synopsis
- * Researchers investigated the G85E-CFTR variant using human nasal epithelial cells and found that the drugs elexacaftor and tezacaftor modestly improved CFTR function, but chronic treatment with ivacaftor had negative effects.
- * The study suggests that combining elexacaftor with a new corrector, ARN23765, can significantly enhance CFTR activity and highlights the need for better drug combinations to help patients with the G85E mutation.
Jellyfish stings can cause acute inflammatory skin lesions that may hesitate in keloids. Pulsed dye laser (PDL) represents one of the most effective treatments for newly developed keloids. Aim of this study was to evaluate the efficacy of PDL on newly developed keloids specifically induced by jellyfish stings in pediatric patients.
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- - A-DRESS (Allopurinol-induced Drug Reaction with Eosinophilia and Systemic Symptoms) is more common in adults but rare in children, with a case reported in a 16-year-old male with a severe reaction, including fever, rash, shock, and eosinophilia.
- - The patient's condition improved after stopping allopurinol and receiving treatment with intravenous immunoglobulins (IVIG) and corticosteroids, highlighting the importance of quick intervention.
- - This case emphasizes the need for early diagnosis of DRESS in pediatric patients and suggests that IVIG may play a significant role in their treatment.