Publications by authors named "C Passingham"

We evaluated long term outcomes in infants born between 1992 and 2002 with cholestatic liver disease (CLD) who underwent successful liver transplantation (LT). A total of 160 children with CLD were identified: 68 had developmental assessments before and after LT of whom 32 were excluded because they were followed up elsewhere; 16/36 consented to complete measures of IQ, anxiety, depression, health related quality of life (HRQoL), and a habits/employment survey. Illness severity and developmental attainment prior to LT were comparable with the 32 excluded and 20 patients who declined to take part.

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Article Synopsis
  • The study aimed to characterize acute-on-chronic liver failure (ACLF) in children at Birmingham Children's Hospital, focusing on its prevalence, triggers, and outcomes.
  • Over a span of 20 years, 24 children were identified with ACLF; 75% of these cases resulted in death, while 36% underwent liver transplantation, with some also dying post-surgery.
  • Key triggers for ACLF included various forms of sepsis and gastrointestinal bleeding, and those who died exhibited more intensive medical interventions like vasopressor use and ventilation compared to survivors.
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In a community survey 521 women aged 35-59 were selected at random from all patients registered in two groups practices. They were interviewed at home and assessed by means of standardised psychiatric measures and detailed gynaecological inquiry. Levels of psychiatric morbidity were found to be within the expected range for such a sample.

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