Publications by authors named "C Papi"
Garlic ( L.) is a species of the onion family () widely used as a food and a folk medicine. The objective of this study was to determine the effects of AGE (aged garlic extract) on pro-inflammatory genes relevant to COVID-19.
View Article and Find Full Text PDFObjectives: Elderly hospitalized patients with inflammatory bowel disease (IBD) flare and concurrent Clostridioides difficile infection (CDI) are considered at high risk of IBD-related complications. We aimed to evaluate the short, intermediate, and long-term post-discharge complications among these patients.
Methods: A retrospective multicenter cohort study assessing outcomes of elderly individuals (≥60 years) hospitalized for an IBD flare who were tested for CDI (either positive or negative) and discharged.
Article Synopsis
- The incidence of metabolic syndrome (MS) has risen in developed countries due to lifestyle choices, combining various health issues that heighten the risk of diabetes and heart diseases.
- Chronic low-grade inflammation, largely driven by obesity and an increase in visceral fat, plays a vital role in the development of MS and is now recognized as a significant cardiovascular risk factor.
- Psoriasis, an inflammatory skin condition, may be linked to metabolic disorders; improving diet and exercise can enhance psoriasis treatment outcomes, highlighting the potential of gut microbiota as a target for therapeutic interventions.
Purpose Of Review: To provide an overview of the pathogenic mechanisms involved in autoimmune encephalitides mediated by antibodies against neuronal surface antigens, with a focus on NMDAR and LGI1 encephalitis.
Recent Findings: In antibody-mediated encephalitides, binding of IgG antibodies to neuronal surface antigens results in different pathogenic effects depending on the type of antibody, IgG subclass and epitope specificity. NMDAR IgG1 antibodies cause crosslinking and internalization of the target, synaptic and brain circuitry alterations, as well as alterations of NMDAR expressing oligodendrocytes, suggesting a link with white matter lesions observed in MRI studies.
Crohn's disease after surgery: Changes in post-operative management strategies over time and their impact on long-term re-operation rate-A retrospective multicentre real-world study.
Aliment Pharmacol Ther
June 2024
Background: Few data are available addressing the impact of post-operative management of Crohn's disease (CD) on long-term clinical course.
Aim: To assess the evolution of post-operative management strategies over the last 40 years and their impact on the re-operation rate of CD.
Methods: We included 657 patients with CD who had undergone their first radical ileo-caecal resection between 1980 and 2020.