Publications by authors named "C Palle"
Purpose: The Groningen International Study on Sentinel nodes in Vulvar cancer (GROINSS-V)-II investigated whether inguinofemoral radiotherapy is a safe alternative to inguinofemoral lymphadenectomy (IFL) in vulvar cancer patients with a metastatic sentinel node (SN).
Methods: GROINSS-V-II was a prospective multicenter phase-II single-arm treatment trial, including patients with early-stage vulvar cancer (diameter < 4 cm) without signs of lymph node involvement at imaging, who had primary surgical treatment (local excision with SN biopsy). Where the SN was involved (metastasis of any size), inguinofemoral radiotherapy was given (50 Gy).
Background/objective: There is a paucity of data on the management of gastrointestinal (GI) bleeding in patients with Coronavirus disease -2019 (COVID-19) amid concerns about the risk of transmission during endoscopic procedures. We aimed to study the outcomes of conservative treatment for GI bleeding in patients with COVID-19.
Methods: In this retrospective analysis, 24 of 1342 (1.
Prognostic utility of serum YKL-40 in patients with cervical cancer.
Scand J Clin Lab Invest
December 2020
Inflammation is one of the hallmarks of cancer and plays a crucial role in the development and progression. The objective of the present study was to investigate if high serum YKL-40 is related to poor prognosis in cervical cancer (CC) patients. A prospective biomarker study of 116 patients with CC (FIGO stage Ia: = 4; Ib: = 55; II: = 26; III: = 26; IV: = 5) and 152 patients with cervical intraepithelial neoplasia (CIN).
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- The study aimed to analyze cocaine treatment demand across 10 Western European countries from 2011 to 2018, focusing on trends in the proportion of cocaine users among all treatment clients.
- Over 700,000 treatment records were reviewed, revealing that most clients (85%) were male with an average age of 35, and cocaine treatment demand varied significantly by country, peaking at 43.1% in Spain.
- The findings indicated a decline in cocaine-related treatment entrants from 2011 to 2014, followed by a notable increase in 2015, with significant rises in countries like Ireland, France, and England displaying annual percentage changes between 7.0% and
Article Synopsis
- - In 2017, 86.5% of people aged 18-75 in France drank alcohol within the last year, with 40.0% consuming it weekly.
- - About 25% of adults exceeded the recommended low-risk drinking guidelines of no more than 10 drinks weekly and 2 daily.
- - The data shows that women drink less than men, and younger people drink less frequently but in larger amounts compared to older adults; overall, per capita alcohol consumption has decreased significantly since the 1960s but is slowing down in decline.