Publications by authors named "C Palladino"
Catalytic enantioconvergent nucleophilic substitution reactions of alkyl halides are highly valuable transformations, but they are notoriously difficult to implement. Specifically, nucleophilic fluorination is a renowned challenge, especially when inexpensive alkali metal fluorides are used as fluorinating reagents due to their low solubility, high hygroscopicity and Brønsted basicity. Here we report a solution by developing the concept of synergistic hydrogen bonding phase-transfer catalysis.
View Article and Find Full Text PDFWest Nile Virus Encephalitis in a Patient with Chronic Lymphocytic Leukemia.
Mediterr J Hematol Infect Dis
January 2025
Article Synopsis
- The systematic review analyzed HIV drug resistance in Mozambique, finding significant levels of resistance mutations in drug-naive and ART-experienced individuals, particularly to NNRTIs and NRTIs.
- Drug resistance mutations were more prevalent in the region of Beira and among pediatric patients compared to adults and pregnant women.
- The study emphasizes the need for ongoing surveillance and targeted interventions to improve ART regimens and public health strategies, particularly for vulnerable populations.
Parathyroid carcinoma (PC) is a rare endocrine malignancy that poses significant diagnostic challenges due to its resemblance to benign conditions. This case series describes the clinical presentation, diagnosis, management, and short-term outcomes of four male patients (aged 54, 65, 73, and 74 years) with primary hyperparathyroidism and hypercalcemia. The preoperative diagnosis of PC remains challenging; suspicion should arise in cases of severe hypercalcemia, elevated parathyroid hormone levels, and the presence of a mass on imaging or during surgery.
View Article and Find Full Text PDF