Publications by authors named "C Pahlson"

Background: Rickettsia helvetica, a spotted fever rickettsia, is transmitted to humans via ticks in Europe, North Africa, and Asia. The central nervous system is a crucial target for rickettsial diseases, which has been reported for 12 of the 31 species, of which R. helvetica is one.

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In a retrospective study, 36 patients with peripheral facial palsy were serologically evaluated for the presence of spp. and spp. antibodies.

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Article Synopsis
  • Eighteen species of rickettsiae cause infections in humans, with Rickettsia helvetica being transmitted by the Ixodes ricinus tick and linked to illnesses like meningitis and perimyocarditis.
  • The study focused on how R. helvetica survives in human leukemic monocytic cells (THP-1), showing that the bacteria not only survives but also propagates within these cells.
  • The findings highlight that infected monocytes produce TNF-α, which plays a role in host defense and may help the cells avoid apoptosis, underscoring the significance of monocytes in rickettsial disease pathology.
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Vector-borne diseases such as Lyme borreliosis and rickettsioses have been associated with ocular inflammation. Our aim was to study patients with diagnosed uveitis to evaluate serological signs of infection or exposure to these tick-borne agents. Forty-eight patients were prospectively examined with serology together with medical records and a questionnaire concerning previous exposure, diseases, and treatments.

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: African tick-bite fever, caused by , is endemic in rural areas of sub-Saharan Africa and a possible cause of fever in returning Swedish travellers. Two patients are presented, and the advantages and disadvantages of different diagnostic methods are discussed. : Two middle-aged men fell ill with fever after returning home from South Africa.

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