Allergic Contact Dermatitis (ACD) to Topical Products in Orthopedic Surgery: Clinical Characteristics and Treatment Strategies.

The potential for many of the commonly used surgical site wound adhesives, skin antiseptic solutions, topical antibiotics, and suture materials to sensitize and subsequently result in allergic contact dermatitis (ACD) has become increasingly recognized within orthopedic surgery. Particularly with subsequent exposure to the offending allergen, the cutaneous allergic reaction may present in a similar fashion to cellulitis, thus making early differentiation between the two etiologies to initiate the appropriate and timely treatment crucial. Recognition of the characteristic appearance and severity of ACD surrounding a surgical wound often drives the initial management.

Superfluid Fraction in an Interacting Spatially Modulated Bose-Einstein Condensate.

At zero temperature, a Galilean-invariant Bose fluid is expected to be fully superfluid. Here we investigate theoretically and experimentally the quenching of the superfluid density of a dilute Bose-Einstein condensate due to the breaking of translational (and thus Galilean) invariance by an external 1D periodic potential. Both Leggett's bound fixed by the knowledge of the total density and the anisotropy of the sound velocity provide a consistent determination of the superfluid fraction.

Performance of the decarboxylation index to predict CO removal and minute ventilation reduction under extracorporeal respiratory support.

Background: The aim of this study was to assess the interdependence of extracorporeal blood flow (Qec) and gas flow (GF) in predicting CO removal and reduction of minute mechanical ventilation under extracorporeal respiratory support.

Methods: All patients who benefited from V-V ECMO and high-flow ECCO R in our intensive care unit over a period of 18 months were included. CO removal was calculated from inlet/outlet blood port gases during the first 7 days of oxygenator use.

Acquisition of extended-spectrum cephalosporin-resistant Gram-negative bacteria: epidemiology and risk factors in a 6-year cohort of 507 severe trauma patients.

Objectives: Severe trauma patients are at higher risk of infection and often exposed to antibiotics, which could favor acquisition of antimicrobial resistance. In this study, we aimed to assess prevalence, acquisition, and factors associated with acquisition of extended-spectrum cephalosporin-resistant Gram-negative bacteria (ESCR-GNB) in severe trauma patients.

Methods: We conducted a retrospective monocentric cohort study in a French level one Regional Trauma Centre between 01 January 2010and 31 December 2015.

Mathematical modelling of oxygenation under veno-venous ECMO configuration using either a femoral or a bicaval drainage.

Background: The bicaval drainage under veno-venous extracorporeal membrane oxygenation (VV ECMO) was compared in present experimental study to the inferior caval drainage in terms of systemic oxygenation.

Method: Two mathematical models were built to simulate the inferior vena cava-to-right atrium (IVC → RA) route and the bicaval drainage-to-right atrium return (IVC + SVC → RA) route using the following parameters: cardiac output (Q), IVC flow/Q ratio, venous oxygen saturation, extracorporeal pump flow (Q), and pulmonary shunt (PULM-Shunt) to obtain pulmonary artery oxygen saturation (SO) and systemic blood oxygen saturation (SaO).

Results: With the IVC → RA route, SO and SaO increased linearly with Q/Q until the threshold of the IVC flow/Q ratio, beyond which the increase in SO reached a plateau.