Prognostic signature based on mitochondria- and angiogenesis-related genes associated with immune microenvironment of multiple myeloma.

Introduction: Mitochondria and angiogenesis play key roles in multiple myeloma (MM) development, but their interrelated genes affecting MM prognosis are under-studied.

Methods: We analyzed TCGA_MMRF and GSE4581 datasets to identify four genes - CCNB1, CDC25C, HSP90AA1, and PARP1 - that significantly correlate with MM prognosis, with high expression indicating poor outcomes.

Results: A prognostic signature based on these genes stratified patients into high- and low-risk groups, with the latter showing better survival.

CIDEC/FSP27 exacerbates obesity-related abdominal aortic aneurysm by promoting perivascular adipose tissue inflammation.

Abdominal aortic aneurysm (AAA) is strongly correlated with obesity, partially due to the abnormal expansion of abdominal perivascular adipose tissue (PVAT). Cell death-inducing DNA fragmentation factor-like effector C (CIDEC), also known as fat-specific protein 27 (FSP27) in rodents, is specifically expressed in adipose tissue where it mediates lipid droplet fusion and adipose tissue expansion. Whether and how CIDEC/FSP27 plays a role in AAA pathology remains elusive.

Influence factors of clinical effects on patients with early gastric cancer: A retrospective study.

Background: Identifying factors that influence non-curative resection (NCR) is critical to optimize treatment strategies and improve patient outcomes in patients with early gastric cancer (EGC).

Aim: To investigate the factors influencing the NCR of EGC and to evaluate the predictive value of these factors.

Methods: The clinical data of 173 patients with EGC admitted between July 2020 and July 2023 were retrospectively collected.

Early Division of the Paramedian Forehead Flap: A Systematic Review and Retrospective Analysis.

Objective: To determine whether and when early division of the paramedian forehead flap may be safely performed.

Data Sources: PubMed (NLM), Scopus (Elsevier), and Embase (Elsevier).

Methods: A systematic search of PubMed, Scopus, and Embase was conducted according to PRISMA guidelines.

Construction of Sub-nano Channels of Amino Pillar[6]arene Inspired Biomimetic Porous Roots for Specific Remove of Imazamox.

The root ducts play an important role in the plant's transport of nutrients from the soil. Based on the selective transport characteristics of plant roots, amino pillar[6]arene bionic porous root sub-nano channel membrane were constructed to remove Imazamox. Imazamox (IM) is an effective imidazolinone herbicide frequently utilized in soybean fields to control a wide range of annual grasses and broad-leaved weeds.