Publications by authors named "C P Levi"

Background: Despite evidence supporting interventions that improve outcomes for patients with stroke, their implementation remains suboptimal. Facilitation can support implementation of research into clinical practice by helping people develop the strategies to implement change. However, variability in the amount (dose) and type of facilitation activities/facilitator roles that make up the facilitation strategies (content), may affect the effectiveness of facilitation.

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Article Synopsis
  • Hyperacute cardiac CT is more effective than transthoracic echocardiography in detecting intracardiac thrombus, but its routine use is limited due to costs and risks.
  • A study of 1,136 ischemic stroke or TIA patients found that longer arterial input function (AIF) dispersal times correlate with the presence of thrombus and worse outcomes, with a specific cutoff of 33 seconds indicating higher risk.
  • The findings support using AIF dispersal measurements to help identify patients who may benefit from cardiac imaging, potentially optimizing resource use in stroke management.
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Purpose: This study examined the effect of resistance training (RT) by itself and in combination with supraphysiological administration of nandrolone decanoate (ND) on the inflammatory, apoptotic, and oxidative stress response in cardiac tissue. The effect of the training and androgen intervention on adiponectin expression, a potential cardio protectant was also examined.

Methods: Forty male C57Bl/6J mice, 3 months of age were randomized into four groups (n = 10 per group).

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Background: Variation in stroke treatment metrics highlight a need for approaches to improve clinical processes. Training interventions can improve outcomes, but Australian physician trainees do not currently receive formal process-directed stroke training. Virtual reality (VR) stroke workflow training has proven acceptable, usable, useful and feasible in trial contexts, but how to integrate VR training into physician training remains unclear.

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Article Synopsis
  • The ETERNAL-LVO trial examines the effectiveness and safety of tenecteplase for patients with large vessel occlusion (LVO) within 24 hours of stroke onset, compared to standard care.
  • The study is a randomized phase 3 trial involving patients with anterior circulation LVO and target mismatch on imaging, focusing on those who may need endovascular treatment.
  • Key outcomes include measuring disability at 3 months using the modified Rankin Scale, alongside safety assessments like the incidence of symptomatic intracerebral hemorrhage and overall mortality.
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