Publications by authors named "C P Gale"

Importance: Intraventricular hemorrhage (IVH) has proven to be a challenging and enduring complication of prematurity. However, its association with neurodevelopment across the spectrum of IVH severity, independent of prematurity, and in the context of contemporary care remains uncertain.

Objective: To evaluate national trends in IVH diagnosis and the association with survival and neurodevelopmental outcomes at 2 years of age.

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Background: Breast milk has significant benefits for preterm babies, but 'very preterm' babies are unable to feed directly from the breast at birth. Their mothers have to initiate and sustain lactation through expressing milk for tube feeding until their babies are developmentally ready to feed orally. There are wide disparities between neonatal units in England in rates of breast milk feeding at discharge.

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Objective: Following very preterm birth, some children require ongoing intensive care after the neonatal period and transition directly from neonatal units (NNUs) to paediatric intensive care units (PICUs) around term-corrected age.We aimed to understand, at a national level, characteristics and outcomes of children born very preterm who transitioned directly from NNUs to PICUs.

Design: Retrospective cohort study, using data linkage of National Neonatal Research Database, Paediatric Intensive Care Audit Network and Office for National Statistics datasets.

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Article Synopsis
  • The EuroHeart project aims to establish standardized definitions for outcome measures in cardiovascular clinical studies to enhance the evaluation of medical interventions and care.
  • A group of 82 experts formed five Working Groups to identify key outcome measures for various cardiovascular conditions, using a systematic review and consensus methods to define these measures.
  • In total, 24 mandatory (Level 1) and 48 optional (Level 2) outcome measures were established across five cardiovascular disease areas, providing a foundation for improved research and patient care quality.
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