Publications by authors named "C P G M De Groot"
Article Synopsis
- Income-based disparities in hip fracture treatment and outcomes were examined across six high-income countries, revealing that lower-income individuals generally faced worse health outcomes.
- The study indicated that low-income populations had higher incidence rates of hip fractures and worse 1-year mortality compared to their high-income counterparts, with the most pronounced difference in Israel.
- Overall, high-income patients experienced shorter hospital stays, lower readmission rates, and quicker surgery times, highlighting the significant impact of income on healthcare quality and access for older adults with hip fractures.
Objective: To explore the personal experiences of women faced with the decision to continue a triplet pregnancy or undergo multifetal pregnancy reduction.
Methods: A qualitative study with semi-structured interviews was conducted between October 2021 and April 2023. Participants included women who continued a triplet pregnancy, and those who underwent multifetal pregnancy reduction from triplet to twins or singletons, 1-6 years post-decision.
Across the lifespan, diet and physical activity profiles substantially influence immunometabolic health. DNA methylation, as a tissue-specific marker sensitive to behavioral change, may mediate these effects through modulation of transcription factor binding and subsequent gene expression. Despite this, few human studies have profiled DNA methylation and gene expression simultaneously in multiple tissues or examined how molecular levels react and interact in response to lifestyle changes.
View Article and Find Full Text PDFTo assess the cost-effectiveness of low-dose aspirin compared to placebo for the prevention of recurrent preterm birth from a healthcare perspective. This was a cost-effectiveness analysis alongside a multicenter, randomized, double-blinded, placebo-controlled trial. We included women with a singleton pregnancy and a previous spontaneous preterm birth <37 weeks of gestation of a singleton.
View Article and Find Full Text PDFObjectives: The primary aim of this study was to assess differences in melanoma recurrence between patients conceiving spontaneously versus those undergoing assisted reproductive technology (ART) and to determine use of ART in post-melanoma patients. A secondary aim was to describe the use of immunotherapy as a novel treatment regimen for metastatic melanoma in a cohort of fertile patients.
Design: This study is a 30-year analysis including data from a single-center questionnaire and a retrospective cohort study.