Pharmacogenetic Testing in Treatment-resistant Panic Disorder: a Preliminary Analysis.

Background: Many pharmacological treatments are considered effective in the treatment of panic disorder (PD), however, about 20 to 40% of the patients have treatment-resistant PD. Pharmacogenetics could explain why some patients are treatment-resistant.

Objective: Our objective was to gather preliminary data on the clinical usefulness of pharmacogenetic testing in this disorder.

Effects of Speed-Based Interventions to Reduce Bradykinesia in Individuals with Parkinson's Disease: A Systematic Review Protocol.

Background/objectives: Bradykinesia is considered one of the most disabling motor symptoms in individuals with Parkinson's disease (PD). Speed-based interventions are promising for reducing bradykinesia in this population. This systematic review aims to describe speed-based interventions that have been employed for reducing bradykinesia in individuals with PD and verify their effects.

Prevalence of sensory impairments and its contribution to functional disability in individuals with acute stroke: A cross-sectional study.

Background: Although the literature suggests high prevalences of sensory impairments after stroke, the independent contribution of sensory modalities to functionality needs further investigation.

Objective: To identify the prevalence and characterize the sensory impairment in adults with stroke and to verify the contribution of proprioceptive and exteroceptive impairments to their functional disability.

Methods: Exploratory cross-sectional study conducted in a hospital stroke unit.

Emergence of in Minas Gerais, Brazil: Genomic Surveillance to inform Rapid Public Health Responses.

poses a significant global health threat due to its multidrug-resistance and outbreak potential. In this study, we report its emergence in Minas Gerais, Brazil, supported by genomic surveillance that identified Clade-IV isolates, suggested a potential introduction from Colombia, and detected a missense mutation associated with azole resistance.

Stroke in Brazil: prevalence, activity limitations, access to healthcare, and physiotherapeutic treatment.

Background:  Stroke remains a public health problem, reported as the third cause of disability. Among survivors, the ability to perform usual daily activities may be reduced, requiring rehabilitation.

Objective:  To investigate the prevalence of self-reported stroke, the accessibility of healthcare, and the degree and percentage of patients with limitations in usual activities who are unassisted by physiotherapeutic treatment in different regions of the country.