APENDIC-RADS: an ultrasound reporting system for the diagnosis of acute appendicitis.

Objective: Abdominal ultrasonography is widely used to evaluate suspected cases of appendicitis. Objective descriptions of the direct and indirect signs of appendicitis result in varied assessments of its likelihood. This study introduces the Appendix Imaging Reporting and Data System (APENDIC-RADS) to standardize the reporting of appendix ultrasound findings.

Unveiling the Colors of Mustelids: A Historical Review on the Emergence of Chromatic Disorders and Their Ecological Effects in Mustelids Worldwide with Report of the First Case of Erythrism in Eira barbara (Carnivora, Mustelidae).

Mustelidae is the largest and most diverse family within the order Carnivora, encompasses 65 species and 22 genera, and is widely distributed around the world. Mustelids exhibit a multiplicity of coloration patterns, ranging from darker tones, such as black and brown, to lighter tones, such as pale yellow and white. Anomalous colorations in wild mustelids are occasionally reported, but these records are still poorly discussed in the scientific literature and are often subject to misidentification and/or incorrect terminology.

Effect of Sexual Partnerships on Zika Virus Transmission in Virus-Endemic Region, Northeast Brazil.

The epidemiologic effects of Zika virus (ZIKV) sexual transmission in virus-endemic countries remain unclear. We conducted a 2-level, linear mixed-effects logistic regression analysis by using a recently acquired population-based ZIKV and chikungunya virus (CHIKV) serologic dataset obtained from persons residing in Northeast Brazil (n = 2,070 participants). We adjusted mathematical models for housing type and age of participants; the models indicated a significantly higher likelihood of ZIKV seropositivity among persons engaged in a sexual relationship within the same household (odds ratio 1.

Enhanced Synergistic Efficacy Against Breast Cancer Cells Promoted by Co-Encapsulation of Piplartine and Paclitaxel in Acetalated Dextran Nanoparticles.

Malignant breast tumors constitute the most frequent cancer diagnosis among women. Notwithstanding the progress in treatments, this condition persists as a major public health issue. Paclitaxel (PTX) is a first-line classical chemotherapeutic drug used as a single active pharmaceutical ingredient (API) or in combination therapy for breast cancer (BC) treatment.

CCR2+ monocytes are dispensable to resolve acute pulmonary Pseudomonas aeruginosa infections in WT and Cystic Fibrosis mice.

Extravasation of CCR2-positive monocytes into tissue and to the site of injury is a fundamental immunological response to infections. Nevertheless, exuberant recruitment and/or activity of these monocytes and monocyte-derived macrophages can propagate tissue damage, especially in chronic inflammatory disease conditions. We have previously shown that inhibiting the recruitment of CCR2-positive monocytes ameliorates lung tissue damage caused by chronic neutrophilic inflammation in cystic fibrosis (CF) mouse models.